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Louis Pasteur and Germ Theory
Starter: Find Someone Who?
BBC on Pasteur
BBC  Bitesize on Pasteur
Activity 2 Pasteur Quiz
Activity 3: Crossword
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WALT: Why is Louis Pasteur famous in the history of medicine?
WILFs: Can describe the story of Louis Pasteur and germ theory (C)
Can explain which factors were important in germ theory (B)... can evaluate the importance of Pasteur's contribution to the history of medicine (A).. can evaluate who was the most important individual in the history of medicine (A*)


An Investigation into 'microbe man'

Louis Pasteur (1822 - 1895)
For centuries doctors had tried to find out how disease was caused. In the mid-19th century, many people in Britain still believed in Miasma, the idea that disease was caused by polluted air. The real breakthrough in understanding the cause of disease was made not by a doctor, but a chemist called Louis Pasteur.
Who was Louis Pasteur?
Louis Pasteur was a French chemist working as a teacher in a university. He was asked by a wine company to explain why some wine turned sour whilst it was being made. Pasteur's research discovered that there were germs in the air that could cause liquids to go off.

What did he do next?
Having discovered that 'bad' wine had germs in it which could be seen through a microscope, Pasteur developed a process for killing the germs by boiling the wine and then cooling it down. He called this process 'pasteurisation'. Pasteur then set about proving that the germs came from the air and could therefore be prevented from entering the liquid in the first place. He demonstrated this by sealing a quantity of a liquid in an airtight jar and leaving another quantity exposed to the air. Pasteur now used his discovery to help treat diseases. He knew that the British doctor Edward Jenner had developed a process of vaccination against the killer disease, smallpox. Pasteur believed that his germ theory could be used to explain how vaccination worked. He examined the blood of healthy people and compared it with the blood of people with various diseases. He observed that when people were infected with disease their blood contained lots of germs.

What new ideas did Pasteur develop?
The process of boiling a liquid to destroy germs is still used today; most dairy products are pasteurised. Pasteur went on to discover vaccinations for chicken pox, cholera, diphtheria, anthrax and rabies. However, not all of Pasteur's ideas were accepted. He recommended that surgical instruments be boiled before an operation to kill any germs on them, but most surgeons ignored this advice. This had to wait until aseptic surgery developed in the 20th century.

How important was Pasteur?
Pasteur's work was revolutionary in discovering the link between germs and disease. This led the way for Robert Koch to later discover how each type of germ caused specific disease and who established a complete germ theory of disease

Lesson 1 Development
Starter: Connect the learning with Find Someone Who

1. Watch the clip using a table take some notes

What did Pasteur discover and how did he do it?

What factors were important?



2. Share you notes with your table and use your books to add detail
3. Table Stand and Share
Investigate the PPT and add to your lists
4. Jenner and Pasteur Quiz Quiz Trade (question cards from Mr Walker)
5. Plenary - form 2 circles and Paraphrase passport today's WALT questions
Lesson 2 Development
1. Starter - Quiz quiz Trade - cards from Mr Walker
2. With your last partner Mix Pair Share
a) How important was Edward Jenner to the history of medicine?
b) How important was Louis pasteur to the history of medicine?
c) Who was most important Jenner or Pasteur?
3. Find a new partner and take them to a computer
4. Read and take notes from the PPT then Rally Coach activities 2 and 3
5. Plenary - choose on person from the history of medicine ... Draw a picture to show them and their discovery... No words no numbers... Then share X 3

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